Our 10 Best Liver Supplements For Dogs To Buy In 2025

Best Liver Supplements For Dogs
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Dogs need a healthy liver for overall well-being. Liver supplements can support liver function and promote vitality.

Choosing the best liver supplements for your dog ensures a healthy life. A dog’s liver plays a crucial role in detoxifying the body and aiding digestion. Supplements can enhance liver health, supporting its natural functions. Many dogs face liver issues due to toxins or poor diet.

A good supplement can make a difference. Look for ingredients like milk thistle, turmeric, and dandelion root. These are known for their liver-boosting properties. Always consult your vet before introducing new supplements. Your dog’s health is important, and finding the right liver support can improve their quality of life. Keep your dog’s liver in top shape for a happier, healthier pet.

Our Picks

1Zesty Paws Liver Support Supplement for Dogs - with Milk ...
Top Pick

Zesty Paws Liver Support Supplement for Dogs – with Milk …

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2Milk Thistle for Dogs - 120 Chewable Tablets - Silymarin ...
Best Quality

Milk Thistle for Dogs – 120 Chewable Tablets – Silymarin …

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3Nutramax Denamarin Liver Health Supplement for Dogs, With S-Adenosylmethionine (SAMe) ...
Recommended

Nutramax Denamarin Liver Health Supplement for Dogs, With S-Adenosylmethionine (SAMe) …

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4Nutramax Laboratories Denamarin Liver Health Supplement for Medium Dogs - ...

Nutramax Laboratories Denamarin Liver Health Supplement for Medium Dogs – …

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5Nutramax Laboratories Denamarin Liver Health Supplement for Large Dogs - ...

Nutramax Laboratories Denamarin Liver Health Supplement for Large Dogs – …

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6LiverTrio+ Comprehensive Liver Support Supplement for Large Dogs. Flavorful Chewable ...

LiverTrio+ Comprehensive Liver Support Supplement for Large Dogs. Flavorful Chewable …

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7Wonder Paws Milk Thistle, Liver Support for Dogs, Supports Kidney ...

Wonder Paws Milk Thistle, Liver Support for Dogs, Supports Kidney …

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8Nutramax Laboratories Denamarin Liver Health Supplement for Small Dogs and ...

Nutramax Laboratories Denamarin Liver Health Supplement for Small Dogs and …

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9Natural Dog Company Stinky Liver & Kidney Supplement Chews, Complete ...

Natural Dog Company Stinky Liver & Kidney Supplement Chews, Complete …

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10Vet Classics Liver Support Pet Health Supplement for Dogs, Cats ...

Vet Classics Liver Support Pet Health Supplement for Dogs, Cats …

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Top 10 Liver Supplements For Dogs Of 2025

Top Pick

Zesty Paws Liver Support Supplement for Dogs - with Milk Thistle Extract, Turmeric Curcumin, Choline - Soft Chew Formula - for Dog Liver Function

1. Zesty Paws Liver Support Supplement for Dogs – with Milk Thistle Extract, Turmeric Curcumin, Choline – Soft Chew Formula – for Dog Liver Function

  • Brand: Zesty Paws
  • Manufacturer: Zenwise Health LLC
  • Dimensions: Height: 4.0 inches Width: 3.5 inches Length: 3.5 inches Weight: 0.7936641432 pounds `

Discover Zesty Paws Liver Support Supplement for Dogs, designed to enhance your pet’s liver health. Packed with Milk Thistle Extract, this formula helps protect liver function. Turmeric Curcumin adds powerful antioxidants for overall wellness. Choline supports normal liver activity and metabolism. Soft chews make it easy for dogs to enjoy their daily supplement. Give your furry friend the best care with these tasty, beneficial chews.

Advantages

  • Zesty Paws Liver Support Supplement offers essential liver health support.
  • Milk Thistle Extract aids in detoxifying and protecting the liver.
  • Turmeric Curcumin helps reduce inflammation and boosts overall liver function.
  • Choline promotes healthy liver cell maintenance and regeneration.
  • Soft chew formula ensures easy consumption and dog-friendly taste.

Our Recommendations

Our dog loves Zesty Paws Liver Support Supplement. The soft chews make it easy to give. No more messy powders. Milk thistle extract supports liver health. Turmeric curcumin adds antioxidants. Choline helps with digestion and liver function. Noticeable improvement in energy and mood. Our pup seems happier. He runs around more now. Simple formula that works. Great for picky eaters. He enjoys the taste of these chews. Highly recommend this product for dogs needing liver support. Peace of mind knowing it’s natural.

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Best Quality

Milk Thistle for Dogs - 120 Chewable Tablets - Silymarin - Liver and Kidney Support with EPA & DHA - Detox - Liver Supplement for Dogs with Choline and L-Arginine

2. Milk Thistle for Dogs – 120 Chewable Tablets – Silymarin – Liver and Kidney Support with EPA & DHA – Detox – Liver Supplement for Dogs with Choline and L-Arginine

  • Brand: Coco and Luna
  • Manufacturer: VITA PET LIFE LLC
  • Dimensions: Weight: 0.25 pounds `

Enhance your dog’s health with Milk Thistle chewable tablets. These tablets support liver and kidney function effectively. Packed with silymarin, they help detox and maintain a healthy liver. EPA and DHA contribute to overall well-being. Choline and L-Arginine provide essential nutrients for your dog’s body. Easy-to-administer tablets make caring for your pet a breeze.

Advantages

  • Supports liver health with silymarin for a happier dog.
  • Enhances kidney function, promoting overall well-being.
  • Includes EPA and DHA for a healthy, shiny coat.
  • Detoxifies the body, removing harmful substances effectively.
  • Choline and L-Arginine boost energy and vitality naturally.

Our Recommendations

Our dog loves the Milk Thistle chewable tablets. Easy to feed. He thinks it’s a treat! His energy levels are higher. Runs and plays more. Seems happier and healthier. We’ve noticed a shinier coat. Smooth and soft. Friends keep complimenting it. Liver and kidney support is important. This supplement delivers. It gives peace of mind. Tablets are packed with silymarin. Helps detox. Supports overall health. Choline and L-Arginine are beneficial. Helps maintain good organ function. Our vet approves. EPA & DHA are crucial. Boosts immunity. Keeps our dog’s health in check. Highly recommend this product. Simple way to support your dog’s health.

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Recommended

Nutramax Denamarin Liver Health Supplement for Dogs, With S-Adenosylmethionine (SAMe) and Silybin, 30 Chewable Tablets

3. Nutramax Denamarin Liver Health Supplement for Dogs, With S-Adenosylmethionine (SAMe) and Silybin, 30 Chewable Tablets

  • Brand: Nutramax Laboratories
  • Manufacturer: Nutramax Laboratories Veterinary Sciences, Inc.
  • Color: beige
  • Dimensions: Height: 4.0 inches Width: 2.5 Inches Length: 2.5 Inches Weight: 225.0 Milligrams `

Nutramax Denamarin provides essential liver support for dogs with its blend of SAMe and Silybin. These chewable tablets are easy for dogs to take, making supplementation stress-free. SAMe helps boost liver function, promoting overall health. Silybin, a milk thistle extract, supports liver detoxification and protects liver cells. Perfect for dogs needing extra liver care. Give your dog the support they deserve with Nutramax Denamarin.

Advantages

  • Promotes liver health with SAMe and Silybin ingredients. Supports overall well-being.
  • Enhances antioxidant levels, aiding in liver cell repair. Keeps your dog active.
  • Easy-to-administer chewable tablets. Makes daily supplementation simple.
  • Helps maintain optimal liver function. Vital for your dog’s health.
  • Trusted by veterinarians for liver support. Ensures peace of mind.

Our Recommendations

Our dog loves Nutramax Denamarin Liver Health Supplement. The chewable tablets are easy for him to take. His energy levels have noticeably increased. His coat looks shinier and healthier. We noticed a positive change in his digestion too. SAMe and Silybin seem to work wonders for liver support. His vet recommended it, and we’re glad we listened. A reliable product for supporting liver health in dogs. Simple and effective, these tablets are a staple in our dog’s diet. Highly recommended for any pet owner.

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Nutramax Laboratories Denamarin Liver Health Supplement for Medium Dogs - With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets

4. Nutramax Laboratories Denamarin Liver Health Supplement for Medium Dogs – With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets

  • Brand: Nutramax Laboratories
  • Manufacturer: Lambriar Vet – Dropship
  • Color: blue
  • Dimensions: Height: 1.4 inches Width: 3.6 inches Length: 5.6 inches Weight: 0.1 pounds `

Discover Nutramax Laboratories Denamarin, a top choice for supporting liver health in medium dogs. This supplement combines S-Adenosylmethionine (SAMe) and Silybin for effective liver support. Easy to administer tablets make it convenient for pet owners. Help your dog maintain optimal liver function with this trusted formula. A healthy liver means a happy, energetic dog. Choose Denamarin for peace of mind and your dog’s well-being.

Advantages

  • Supports liver health with powerful ingredients like SAMe and Silybin.
  • Enhances antioxidant activity, protecting liver cells from damage.
  • Boosts bile flow, aiding digestion and nutrient absorption.
  • Promotes overall vitality and well-being in medium-sized dogs.
  • Easy-to-administer tablets make daily supplementation stress-free.

Our Recommendations

Our dog’s health improved with Denamarin. His energy levels are higher. Coat looks shinier and healthier. A noticeable difference in liver function. Vet recommended it. Easy to give and swallow tablets. Worth every penny. Highly recommend for medium dogs. Peace of mind knowing our dog is healthier.

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Nutramax Laboratories Denamarin Liver Health Supplement for Large Dogs - With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets(Pack of 1)

5. Nutramax Laboratories Denamarin Liver Health Supplement for Large Dogs – With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets(Pack of 1)

  • Brand: Nutramax Laboratories
  • Manufacturer: Nutramax Laboratories Veterinary Sciences, Inc.
  • Color: white
  • Dimensions: Height: 3.625 inches Width: 1.875 inches Length: 1.875 inches

Nutramax Laboratories Denamarin supports liver health in large dogs with a unique formula. S-Adenosylmethionine (SAMe) helps maintain liver cell function. Silybin, derived from milk thistle, boosts antioxidant activity. Easy-to-administer tablets make daily supplementation simple. Trusted by pet owners for effective liver care.

Advantages

  • Supports liver function naturally with SAMe and Silybin ingredients. Perfect for large dogs needing extra care.
  • Promotes detoxification by enhancing liver’s ability to filter toxins. Keeps your dog’s liver healthy.
  • Improves antioxidant levels, helping protect liver cells from damage. Essential for maintaining vitality.
  • Easy-to-administer tablets ensure hassle-free supplementation. Convenient for busy pet owners.
  • Trusted by veterinarians for liver health management in dogs. Peace of mind for pet parents.

Our Recommendations

Denamarin has greatly improved my dog’s liver health. Easy to give. The tablets are small and palatable. My large dog seems more energetic since starting this supplement. Vital signs have improved. Noticeable difference in his behavior. Vet recommended Denamarin, and it truly works. SAMe and Silybin are powerful ingredients. Great for liver support. Packaging is convenient. One pack lasts a month. Reliable product for maintaining liver wellness in dogs.

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LiverTrio+ Comprehensive Liver Support Supplement for Large Dogs. Flavorful Chewable Tablets Combining Same, SPC, Silybin A+B, + Glutathione 30Ct (Large)

6. LiverTrio+ Comprehensive Liver Support Supplement for Large Dogs. Flavorful Chewable Tablets Combining Same, SPC, Silybin A+B, + Glutathione 30Ct (Large)

  • Brand: LiverTrio+
  • Manufacturer: 1Family 1Health Pharmacy
  • Color: Orange
  • Dimensions: Weight: 0.14375 pounds `

LiverTrio+ offers large dogs comprehensive liver support with flavorful chewable tablets. Packed with beneficial ingredients like SAMe, SPC, Silybin A+B, and Glutathione, it’s designed for optimal liver health. Dogs enjoy the taste while benefiting from essential nutrients. Easy to administer and formulated with care. Perfect for enhancing your dog’s vitality and well-being.

Advantages

  • Promotes liver health in large dogs with powerful ingredients.
  • Chewable tablets are easy and enjoyable for dogs to consume.
  • Boosts detoxification processes with a blend of essential compounds.
  • Supports overall vitality and energy in your furry friend.
  • Combines SAMe, SPC, Silybin, and Glutathione for comprehensive liver care.

Our Recommendations

LiverTrio+ has been a lifesaver for my large dog. These chewable tablets are easy to give and he loves the flavor. His energy levels have improved noticeably. The combination of ingredients like Same, SPC, Silybin A+B, and Glutathione is impressive. His coat looks shinier, and he seems more comfortable. Highly recommend for any dog owner seeking liver support.

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Wonder Paws Milk Thistle, Liver Support for Dogs, Supports Kidney Function for Pets, Detox, Hepatic Support, with Wild Alaskan Salmon Oil & Curcumin, Omega 3 EPA & DHA (2 Oz)

7. Wonder Paws Milk Thistle, Liver Support for Dogs, Supports Kidney Function for Pets, Detox, Hepatic Support, with Wild Alaskan Salmon Oil & Curcumin, Omega 3 EPA & DHA (2 Oz)

  • Brand: WONDER PAWS
  • Manufacturer: Wonder Paws
  • Color: Yellow
  • Dimensions: Weight: 0.125 pounds `

Enhance your dog’s well-being with Wonder Paws Milk Thistle. Supports liver health and kidney function effectively. This blend includes Wild Alaskan Salmon Oil and Curcumin for added benefits. Rich in Omega 3 EPA and DHA, ensuring optimal support. Ideal for detox and hepatic care, promoting vitality in pets. Easy to use and formulated for results.

Advantages

  • Dogs deserve healthy liver function support. Wonder Paws Milk Thistle delivers this. The blend promotes kidney health in pets. Essential for detox, it aids the body’s natural process.
  • Wild Alaskan Salmon Oil enhances the formula. Rich in Omega 3 EPA and DHA. Supports skin and coat health. Curcumin adds extra antioxidant benefits. Protects cells from damage.
  • Easy-to-use 2 Oz size fits any pet routine. Perfect for daily use. Simple addition to meals or treats. Convenient for busy pet owners. Supports overall wellness.

Our Recommendations

Wonder Paws Milk Thistle has transformed my dog’s health. His energy levels are noticeably higher. He seems happier and more active. The blend with Wild Alaskan Salmon Oil is excellent. His coat is shinier and softer. Friends comment on his healthy glow. Omega 3 EPA & DHA really support kidney function. My dog’s digestion is better. No more upset stomachs. Curcumin adds great detox benefits. His liver health has improved. Vet visits are less stressful now. Highly recommend for any dog owner. Easy to use and effective. My dog loves the taste too!

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Nutramax Laboratories Denamarin Liver Health Supplement for Small Dogs and Cats - With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets

8. Nutramax Laboratories Denamarin Liver Health Supplement for Small Dogs and Cats – With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets

  • Brand: Nutramax Laboratories
  • Manufacturer: Nutramax Laboratories Veterinary Sciences, Inc.
  • Color: white
  • Dimensions: Height: 3.625 inches Width: 1.875 inches Length: 1.875 inches

Nutramax Laboratories Denamarin Liver Health Supplement supports liver health in small dogs and cats. It contains S-Adenosylmethionine (SAMe), which helps maintain liver cell function. Silybin enhances antioxidant protection, improving liver health. Easy-to-administer tablets make it convenient for pet owners. Ideal for pets needing extra liver support. Trusted by veterinarians for quality and effectiveness.

Advantages

  • Denamarin supports liver health in small pets effectively. Its ingredients, SAMe and Silybin, are known to improve liver function.
  • Easy-to-administer tablets simplify daily supplementation. No struggle with your pet.
  • Helps enhance antioxidant activity in the body. Promotes better overall health.
  • Designed for small dogs and cats. Tailored to suit their specific needs.
  • Promotes liver cell regeneration, aiding in recovery. Supports a happier pet life.

Our Recommendations

Our little dog loves Denamarin tablets. Easy to give and he doesn’t even notice them. His energy improved greatly. Vet recommended this supplement. Supports liver health like a charm. Peace of mind for pet owners. Tablets are a good size for small pets. No struggle to get our cat to take them. Noticeable changes in behavior and mood. More playful and active. Happy to have found this product. The packaging is neat. Keeps tablets fresh. A must-have for any pet owner caring about liver health.

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Natural Dog Company Stinky Liver & Kidney Supplement Chews, Complete Detox Cleanse & Major Organ Support, Advanced Liver and Kidney Health Support for Dogs, Enhances Digestion and Immunity 90 Chews

9. Natural Dog Company Stinky Liver & Kidney Supplement Chews, Complete Detox Cleanse & Major Organ Support, Advanced Liver and Kidney Health Support for Dogs, Enhances Digestion and Immunity 90 Chews

  • Brand: Natural Dog Company
  • Manufacturer: Natural Dog Company
  • Color: Liver & Kidney
  • Dimensions: Weight: 0.59525 pounds `

Give your dog the gift of health with Natural Dog Company Stinky Liver & Kidney Supplement Chews. These chews support liver and kidney health, promoting a complete detox cleanse for your furry friend. Enhance your dog’s digestion and immunity with each bite-sized treat. Crafted for easy consumption, they make supporting major organ health simple and enjoyable. With 90 chews per pack, your pet will enjoy long-lasting benefits. Perfect for maintaining your dog’s overall well-being and vitality.

Advantages

  • Boosts liver and kidney health naturally. Keeps your dog feeling great.
  • Supports digestion and immunity with ease. Perfect for a healthier pup.
  • Promotes detox cleanse effectively. Helps remove harmful toxins.
  • Made with stinky liver, dogs love the taste. Easy to feed.
  • Advanced organ support. Essential for your dog’s overall wellness.

Our Recommendations

These chews work wonders for my dog’s health. Her energy levels have improved remarkably. She seems happier and more active. The natural ingredients make me feel confident in what I’m giving her. No more worrying about harsh chemicals. Her digestion has noticeably improved. Less bloating and discomfort. She seems more comfortable after meals. Immunity boost is evident. She hasn’t been sick since starting these chews. Her coat even looks shinier. Overall, these supplement chews are great for her liver and kidney health. A happy and healthier pup!

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Vet Classics Liver Support Pet Health Supplement for Dogs, Cats – Liver Functions – B-Vitamins, Glutathione, Milk Thistle – Soft Tablets, Chews – 60 Soft Chews

10. Vet Classics Liver Support Pet Health Supplement for Dogs, Cats – Liver Functions – B-Vitamins, Glutathione, Milk Thistle – Soft Tablets, Chews – 60 Soft Chews

  • Brand: Vet Classics
  • Manufacturer: Vet Classics
  • Dimensions: Weight: 0.3968320716 Pounds `

Discover the benefits of Vet Classics Liver Support Pet Health Supplement. Designed for both dogs and cats, it promotes healthy liver function. Packed with B-vitamins, Glutathione, and Milk Thistle, these ingredients work together to support liver health. Soft chews make it easy and enjoyable for your pet. Each bottle contains 60 soft chews, perfect for daily use. Ensure your furry friend stays healthy and active with this supportive supplement.

Advantages

  • Supports liver health with essential B-vitamins and glutathione.
  • Milk thistle aids in detoxifying and protecting liver functions.
  • Soft chews are easy for pets to consume daily.
  • Ideal for both dogs and cats, ensuring versatility.
  • Promotes overall well-being, enhancing your pet’s quality of life.

Our Recommendations

Our Labrador loves Vet Classics Liver Support Chews. These soft tablets make it easy to support his liver health. Milk thistle and B-vitamins work wonders. His energy levels are up, and he seems happier. The chews are easy to give. No stress at all during feeding time. Great for both dogs and cats. A must-have for any pet owner concerned about liver health. Highly recommend this product for its quality ingredients and effectiveness. Our furry friend is thriving.

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Frequently Asked Questions

What Are Liver Supplements For Dogs?

Liver supplements support your dog’s liver health. They help detoxify, improve liver function, and protect cells.

Are Liver Supplements Safe For All Dogs?

Most liver supplements are safe for dogs. Consult your vet before starting any new supplement to ensure safety.

How Do I Choose The Best Liver Supplement?

Look for supplements with natural ingredients. Check for vet recommendations and positive reviews from other dog owners.

How Often Should I Give Liver Supplements To My Dog?

Follow the dosage instructions on the product label. Usually, it’s once or twice daily, but consult your vet.

Conclusion

Choosing the best liver supplement for your dog can be a thoughtful decision. Your furry friend deserves the best care. Liver supplements can support their liver function and overall health. It’s important to consider your dog’s specific needs and consult with a vet.

Each supplement has unique benefits. Carefully read labels and reviews. Ensure the supplement is safe and effective. Different dogs may react differently to supplements. Start with a small dosage. Observe any changes in your dog’s behavior or health. Don’t forget regular vet check-ups.

They help monitor your dog’s liver health. Supplements can be a helpful part of a balanced diet. But they don’t replace regular vet care. Keep researching and learning about your dog’s health. Knowledge is power in making informed decisions. Your dog’s health and happiness depend on it.

So, take the time to find the right liver supplement. Your dog will thank you.